As a typical B-Movie it is pretty average, though I think some of the parts were very well cast. The biggest issue was, as an adaptation of the source material, it stunk. Now, this isn't altogether uncommon for adaptations (especially pre-2010), but these days it feels like it falls well short of some of the really good adaptations that have come since.
I feel they went too gritty, too realistic and tweaked too much of the wacky 2000AD-ness out of it. They basically turned it in to pseudo-steampunk WWII looking guys fighting generic zombies.
If you go in expecting a B-Movie with some fan favourite actors in it, then it is basically that. But as a Mutant Chronicles movie, it is not really a good fit.
Now... if we could get Del Toro interested in making a proper adaptation, I think we'd be in for a treat (and we would still likely get Ron Perlman in there

). A proper Mutant Chronicles movie should be a flashy high-action, pulpy thrill-ride with a proper ensemble cast. Grim'n'gritty !WWII B-movie with zombies and drama just don't fit (MC absolutely needs some colour to it; the movie was so bloody grey and brown).